UVRI/Medical Research Council Uganda

HIV Prevention Studies Programme

Dr. Anatoli Kamali, Head of Programme

The HIV Prevention Studies Programme aims to evaluate new preventive interventions against HIV transmission and related infections. The studies are conducted both in Masaka district, approximately 140 km South West of Kampala and in and around Entebbe. In 1994 a cohort of approximately 14,500 adults was established in Masaka district to assess the impact of a strategy for the treatment of sexually transmitted infections (STI) and behavioural interventions on the incidence of HIV infection and other STIs. This has been followed by studies in preparation of other large scale HIV prevention trials.

Completed projects

MDP 301: An international multi-centre randomised controlled trial to evaluate the efficacy and safety of 0.5% and 2% PR0 2000/5 gels for the prevention of vaginally acquired HIV infection

Principal Investigator (Uganda site): Anatoli Kamali
Project leaders: Zacchaeus Anywaine (main trial); Agnes Ssali (social science component)

Collaborating institutions: Mwanza Intervention Trials Unit, Tanzania (MITU); Medical Research Council, Durban, South Africa; Reproductive Health Research Unit, University of Witwatersrand, Johannesburg, South Africa; Wellcome Trust Africa Centre, Mtubatuba, South Africa; more