Dr. Steve Cose
His current research goal is to apply his expertise in fundamental cellular immunology to the investigation of tuberculosis in Uganda, a setting in which this disease is still highly endemic. In his previous posts, he undertook research into lymphocyte migration and trafficking, studies which were performed in mice and gave him key skills in isolating lymphocytes from tissues, multi parameter flow cytometry and immunofluorescence techniques.
He joined the MRC/UVRI research Unit on AIDS in 2009 and his focus has since changed to human Immunology. He is a named co-investigator and project lead on an MRC funded project to look at whether a latent TB infection in mothers affects their infant’s response to BCG. He is also undertaking other projects like the non-specific effects of BCG in infants and a post-mortem study being piloted at Mulago Hospital collaboration with the Pathology Department to look at the immune response to TB in the tissues, the site at where the infection is.